Right now, around 7.2 million Americans live with Alzheimer’s, and the numbers are expected to rise as the population ages. The disease affects one in nine people who are 65 and older, showing just how common and life-changing it can be.
Alzheimer’s and other forms of dementia often begin with mild forgetfulness, but symptoms can develop into confusion, hallucinations, physical stiffness, and even severe anxiety over time. Because of how devastating it can be, any potential method to reduce risk naturally grabs attention.
Investigators at Johns Hopkins Medicine found that hydrogen sulfide — the gas responsible for that familiar terrible smell — may help slow cognitive decline and protect brain cells from damage that leads to Alzheimer’s.
Dr. Bindu Paul, an associate professor and study co-author, explained the findings clearly: “Our new data firmly link aging, neurodegeneration and cell signaling using hydrogen sulfide and other gaseous molecules within the cell.”
They injected the mice with NaGYY, a compound designed to release small amounts of gas molecules throughout the body over time.
After allowing twelve weeks for the compound to work, the scientists ran a series of tests to see how the mice performed.
The mice that received the treatment showed around a 50 percent improvement in both memory and motor skills compared to those that received no treatment at all.
The difference was clear and caught the team’s attention immediately.
It suggested a meaningful connection between hydrogen sulfide and healthier brain function.
“The results showed that the behavioral outcomes of Alzheimer’s disease could be reversed by introducing hydrogen sulfide,” the Johns Hopkins team noted while sharing their findings.
“Understanding the cascade of events is important to designing therapies that can block this interaction like hydrogen sulfide is able to do,” PhD student Daniel Giovinazzo explained when discussing how these interactions could lead to better treatment options in the future.
So the next time you accidentally let one slip, just remember — there might be a tiny silver lining in the science behind it.
